MW 461 Da, Purity >98%. Potent, cell-permeable, reversible, ATP-competitive, and selective PKC inhibitor (IC₅₀ = 15 nM, rat brain PKC). Blocks antigen driven, but not IL-2 induced, T-cell proliferation. Shows less potent apoptotic effects than Ro-31-8220 (ab120374).
The product is subject to the following: Abcam Restricted Use Statement